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May 24, 2012
Jeff Jacoby: The peace process battered Israel's reputation
Michael Muskal: 'Pro-choice' position hits record low, according to poll
Chris Farrell: Are We in a Tech Bubble?
The Kosher Gourmet by Penelope Wall: PHILLY CHEESE STEAKS --- hold the steak!
May 23, 2012
Tony Pugh: More private colleges offering tuition discounts
Mary Beth Franklin: How to Choose the Right Annuity for You
Tina Susman: The wig wasn't enough: Man gets 13 years for posing as his dead mom
The Kosher Gourmet by Emma Christensen:A simple way to do fish right
May 22, 2012
Warren Richey: Can US group challenge overseas surveillance act? Supreme Court to decide
Thomas M. Anderson: Walking Away From a Mortgage
The Kosher Gourmet by Megan Gordon: Enjoy a celebration of the most rich and layered flavors: Black bean, sweet potato and quinoa chili
May 21, 2012
Mark Clayton: Cybersecurity: How US utilities passed up chance to protect their networks
Howard LaFranchi: NATO summit: Who will foot the bill for long-term Afghanistan security?
Chris Farrell : Earn Dividends in Emerging Markets with This WisdomTree ETF
Stephen Whiteside, Ph.D. : Mayo Clinic Medical Edge: Social anxiety disorder --- or just shy?
Guy Jackson : Victim's father regrets death of Lockerbie bomber
The Kosher Gourmet by Mario Batali: Famed chef's veal shoulder farsumagru: A festive meat course for late spring
May 18, 2012
Rabbi Berel Wein: Striving: The People of the Book's Book for (All of) the People
Steven Goldberg: 5 Great Stock Picks and the Exchange-Traded Fund that Owns Them
Mary Pickett, M.D.: Ask the Harvard Experts: Don't be forced into gluten-free lifestyle based merely on a doctor's false-positive test
The Kosher Gourmet by Carolyn Malcoun: DIY healthy lunchbox treats: HOMEMADE FRUIT BARS for kids and brown-bagging adults alike
May 17, 2012
Warren Richey: Teacher fired for being unwed and pregnant can sue religious school, court rules
Josh Mitnick: Netanyahu's 'centrist' coalition is already proving it's anything but
Steven Goldberg: Earn Dividends in Emerging Markets with This WisdomTree ETF
Amina Khan: Research links coffee to lower death rates
The Kosher Gourmet by Faith Duran : Cheesy Potato Breakfast Casserole with Cheddar and Sun-Dried Tomatoes
May 16, 2012
Carmen Terzic, M.D., Ph.D. : Mayo Clinic Medical Edge: A variety of exercises can help improve balance
Melissa Healy: National strategy on Alzheimer's disease aims to halt it by 2025
The Kosher Gourmet by Joyce White : GOODNESS GRACIOUS: GREENS! 4 winning recipes that are no longer just for down-home folks (Includes expert tips & techniques)
May 15, 2012
Kristen Chick: Obama administration resumes arms sales to Bahrain despite serious unresolved human rights issues. Activists feel abandoned
Pat Mertz Esswein: Homes are now affordable again and mortgage rates are low. What you need to know before you buy
Kathy Kristof: Our Practical Investor Fights Inflation with These 6 Investments
Sue Hubbard, M.D.: The Kid's Doctor: Lactose intolerant young child? Check again
The Kosher Gourmet by Kathy Hunt: Spread a Little Excitement with EXOTIC CONDIMENTS (4 RECIPES)
May 14, 2012
Lisa Gerstner: How to Protect Your Identity, Finances If You Lose Your Phone
Harvard Health Letters: Heart disease and dementia
The Kosher Gourmet by Megan Gordon: MANGO COCONUT OAT MORNING MUFFINS are a bright but hearty delight
May 11, 2012
Jessica L. Anderson: Get the Best Deal on a Used Car
Jett Stone: Forget face-lifts and fake knees. Scientists have seen the fountain of youth --- and it's broccoli
The Kosher Gourmet by Chef Mario Batali: The famed chef's vegetable dish that tastes true to the season: FAVAS AND SUGAR SNAP PEAS WITH POTATOES AND TARRAGON
May 10, 2012
Sergei L. Loiko: Putin sends warning to U.S., NATO in Victory Day speech at Red Square
Mary Rourke: How being a 'mentch' got Vidal Sasoon his start and fighting in Israel's War of Independence provided him with confidence and a strong sense of his own identity
Jeff Bertolucci: Get Home Phone Service for Less Than $10 a Month
The Kosher Gourmet by Betty Rosbottom: Gleaming with its golden, crimson, and snowy white hues, this silken smooth and creamy STRAWBERRY ORANGE TRIFLE looks impressive, but is easy to prepare
May 9, 2012
Sharon Palmer, R.D. How you can reduce your risk -- or delay -- chronic diseases associated with aging
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Jewish World Review
How Stuff Works: How vaccines work
By
Marshall Brain
http://www.JewishWorldReview.com | (MCT)
accines are big news right now. All over town you can find places delivering the normal, seasonal flu vaccine — everywhere from the county health clinic to the local drugstore. There is also a lot of buzz around the special H1N1 vaccine — millions of people are being vaccinated. There is currently an outbreak of the mumps in Brooklyn, N.Y., and surrounding areas because people there weren't vaccinated properly.
At the root of all this is a simple and fascinating technology that takes advantage of a special property of the human immune system. We can understand how it works by looking at the world's first vaccine.
If we could go back in time to the 1700s, the world was a very different place. Infectious diseases ran rampant. Mumps, measles and polio were obvious problems, but there was also a scourge called smallpox. It killed millions. It left many people blind. And those who survived the disease were often left with disfiguring scars from the disease's pustules. These scars have been found on the faces of Egyptian mummies, so we know the disease is thousands of years old.
There was, however, a group of people who seemed to be untouched by smallpox. These people were known as milkmaids — women who milked cows for a living. Their immunity to smallpox was obvious because of their smooth skin. A scientist named Edward Jenner noticed this, and hypothesized that the women were being protected by exposure to cowpox. In other words, the women were getting infected with cowpox, which is a much milder disease than smallpox. Once the women recovered from cowpox, they had somehow acquired immunity to smallpox.
Jenner's breakthrough idea was this: If he were to purposefully infect people with cowpox at a young age, he would be able to protect them from smallpox for life. Jenner called the process vaccination — vacca being the Latin word for cow. James Phipps was the first boy to be vaccinated. Jenner made a small cut on his skin and inserted pus from a cowpox lesion. The boy did get sick with cowpox, and then recovered normally. And he became immune to smallpox in the process. The rest, as they say, is history. The process of vaccination was improved and refined, to the point where today the disease known as smallpox has been completely eradicated.
Why did this work? Jenner had no concept of the actual mechanisms. It would be more than 100 years before scientists discovered viruses. But the mechanism is the basis of all vaccines today. When a human being is infected by any viral disease, the human immune system has to discover and eliminate the virus. Virus particles are extremely small — much smaller than bacteria cells, which are themselves a hundred times smaller than human cells. The virus particles attach to human cells, inject a tiny bit of genetic material and force the cells to manufacture millions of new virus particles.
To eliminate a virus, white blood cells in your body produce antibodies. Antibodies are molecules that cling to virus particles and deactivate them. The clinging antibodies also act like beacons that make it easy for the body to eliminate the virus particles. However, the body does not make antibodies for a specific virus until it gets exposed to the virus. This is why most viral diseases are only caught once in a lifetime.
The idea behind any vaccine, therefore, is to pre-expose the body to a form of the virus so that the body is producing antibodies when the real virus comes along. In the case of smallpox, it turned out that the cowpox virus particles were nearly identical to smallpox virus particles — so close that cowpox antibodies also cling to smallpox virus particles. Once exposed to cowpox, the same antibodies would attack smallpox too. Other vaccines deliver dead virus particles. The body learns to produce antibodies against the dead virus, and then when it sees live virus particles it eliminates them immediately. All vaccines work on this same basic principle, exposing the immune system to the disease in some way so the body learns to produce antibodies. Those antibodies then confer protection against the real disease.
Are vaccines something to be afraid of? Obviously not. We should be far more fearful of the diseases they prevent. Vaccines have made our world a much better place, and when used widely can completely eliminate dangerous and deadly viruses.
Every weekday JewishWorldReview.com publishes what many in the media and Washington consider "must-reading". Sign up for the daily JWR update. It's free. Just click here.
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Previously:
How the smart grid works
How sea level works
How employee screening works
How to avoid catching a cold
How bread works
How a home energy audit works
How Omega-3 fatty acids work
Social networking
How trick birthday candles work
How electric cars like the Nissan Leaf work
How a manned mission to Mars works
How gold works
How bad breath works
How the ultimate sunglasses work
Any rocket is easily converted to a missile
How to have a great staycation
How a black box works
How a solar roof works
How nuclear bombs work
How the Hubble Space Telescope works
How hay fever works
How to know when to rent vs. buy
How swine flu works
How a kidney dialysis machine works
How children die in hot cars
How a trillion dollars works
How electronic cigarettes work
How chimpanzees work
How in vitro fertilization works
How supertankers work
How poisons work
How corn works
How dog ID chips work
How President Obama's limousine works
How emergency power works
How aircraft carriers work
How antibiotics and vaccines work
How mucus works
How iron and steel work
How aspirin works
How igloos work
How the Predator UAV works
How retention ponds work
How water absorbers work
How melamine works
How digital music works
How coal mining works
How an economic depression works
How the liver works
How 3D movies work
How oil pipelines work
How jet packs work
How seismographs work
How Olympic technology works
How Personal Rapid Transit works
How 3G works
How the Global Position System (GPS) works
How octane works
How cruise missiles work
How submarines work
How miles work
How octane works
How food preservation works
How beer works
How holding your breath works
How smoke detectors work
How heat pumps work
How your night vision works
How concentrating solar collectors work
How your key fob works
How the common cold works
How the Large Hadron Collider Works
How making a TV show works
How dry cleaning works
How exoskeletons work
How an oil refinery works
How landfills work
How the Orion spacecraft works
The cutting edge in HDTV
Redefining the CD
How the HDMI cable scam works
How glow-in-the-dark toys work
How the subprime mortgage crisis works
How gift cards work
How Tasers work
How giant TV screens work
How foreclosure works
How Air Force One works
How wildfire fighting works
How vitamins work
How ejection seats work
How reattaching limbs works
How hot air balloons work
How paparazzi work
How counterfeiting works
How CDs work
How the Edsel worked
How Stinger missiles work
How hybrid cars work
How sharks work
How mosquitoes work
How diesel engines work
How water towers work
How the Dawn mission works
How Kassam rockets work
How the North American Eagle works
Why aren't we flying to work?
How tofu and soy milk work
How Colony Collapse Disorder works
How airbags work
How the U.S. income tax works
How gum works
How caffeine works
How Daylight Saving Time works
How a cruise missile works
How snow making works
© 2007, How Stuff Works Inc. Distributed by McClatchy-Tribune Information Services.
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