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Jonathan Tobin: Defending the Right to a Jewish State

Heather Hale: Compliment your kids without giving them big heads

Megan Shauri: 10 ways you are ruining your own happiness

Carolyn Bigda: 8 Best Dividend Stocks for 2015

Kiplinger's Personal Finance editors: 7 Things You Didn't Know About Paying Off Student Loans

Samantha Olson: The Crucial Mistake 55% Of Parents Are Making At Their Baby's Bedtime

Densie Well, Ph.D., R.D. Open your eyes to yellow vegetables

The Kosher Gourmet by Megan Gordon With its colorful cache of purples and oranges and reds, COLLARD GREEN SLAW is a marvelous mood booster --- not to mention just downright delish
April 18, 2014

Rabbi Yonason Goldson: Clarifying one of the greatest philosophical conundrums in theology

Caroline B. Glick: The disappearance of US will

Megan Wallgren: 10 things I've learned from my teenagers

Lizette Borreli: Green Tea Boosts Brain Power, May Help Treat Dementia

John Ericson: Trying hard to be 'positive' but never succeeding? Blame Your Brain

The Kosher Gourmet by Julie Rothman Almondy, flourless torta del re (Italian king's cake), has royal roots, is simple to make, . . . but devour it because it's simply delicious

April 14, 2014

Rabbi Dr Naftali Brawer: Passover frees us from the tyranny of time

Greg Crosby: Passing Over Religion

Eric Schulzke: First degree: How America really recovered from a murder epidemic

Georgia Lee: When love is not enough: Teaching your kids about the realities of adult relationships

Cameron Huddleston: Freebies for Your Lawn and Garden

Gordon Pape: How you can tell if your financial adviser is setting you up for potential ruin

Dana Dovey: Up to 500,000 people die each year from hepatitis C-related liver disease. New Treatment Has Over 90% Success Rate

Justin Caba: Eating Watermelon Can Help Control High Blood Pressure

The Kosher Gourmet by Joshua E. London and Lou Marmon Don't dare pass over these Pesach picks for Manischewitz!

April 11, 2014

Rabbi Hillel Goldberg: Silence is much more than golden

Caroline B. Glick: Forgetting freedom at Passover

Susan Swann: How to value a child for who he is, not just what he does

Cameron Huddleston: 7 Financial Tasks You Should Tackle Right Now

Sandra Block and Lisa Gerstner: How to Profit From Your Passion

Susan Scutti: A Simple Blood Test Might Soon Diagnose Cancer

Chris Weller: Have A Slow Metabolism? Let Science Speed It Up For You

The Kosher Gourmet by Diane Rossen Worthington Whitefish Terrine: A French take on gefilte fish

April 9, 2014

Jonathan Tobin: Why Did Kerry Lie About Israeli Blame?

Samuel G. Freedman: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Jessica Ivins: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Kim Giles: Asking for help is not weakness

Kathy Kristof and Barbara Hoch Marcus: 7 Great Growth Israeli Stocks

Matthew Mientka: How Beans, Peas, And Chickpeas Cleanse Bad Cholesterol and Lowers Risk of Heart Disease

Sabrina Bachai: 5 At-Home Treatments For Headaches

The Kosher Gourmet by Daniel Neman Have yourself a matzo ball: The secrets bubby never told you and recipes she could have never imagined

April 8, 2014

Lori Nawyn: At Your Wit's End and Back: Finding Peace

Susan B. Garland and Rachel L. Sheedy: Strategies Married Couples Can Use to Boost Benefits

David Muhlbaum: Smart Tax Deductions Non-Itemizers Can Claim

Jill Weisenberger, M.S., R.D.N., C.D.E : Before You Lose Your Mental Edge

Dana Dovey: Coffee Drinkers Rejoice! Your Cup Of Joe Can Prevent Death From Liver Disease

Chris Weller: Electric 'Thinking Cap' Puts Your Brain Power Into High Gear

The Kosher Gourmet by Marlene Parrish A gift of hazelnuts keeps giving --- for a variety of nutty recipes: Entree, side, soup, dessert

April 4, 2014

Rabbi David Gutterman: The Word for Nothing Means Everything

Charles Krauthammer: Kerry's folly, Chapter 3

Amy Peterson: A life of love: How to build lasting relationships with your children

John Ericson: Older Women: Save Your Heart, Prevent Stroke Don't Drink Diet

John Ericson: Why 50 million Americans will still have spring allergies after taking meds

Cameron Huddleston: Best and Worst Buys of April 2014

Stacy Rapacon: Great Mutual Funds for Young Investors

Sarah Boesveld: Teacher keeps promise to mail thousands of former students letters written by their past selves

The Kosher Gourmet by Sharon Thompson Anyone can make a salad, you say. But can they make a great salad? (SECRETS, TESTED TECHNIQUES + 4 RECIPES, INCLUDING DRESSINGS)

April 2, 2014

Paul Greenberg: Death and joy in the spring

Dan Barry: Should South Carolina Jews be forced to maintain this chimney built by Germans serving the Nazis?

Mayra Bitsko: Save me! An alien took over my child's personality

Frank Clayton: Get happy: 20 scientifically proven happiness activities

Susan Scutti: It's Genetic! Obesity and the 'Carb Breakdown' Gene

Lecia Bushak: Why Hand Sanitizer May Actually Harm Your Health

Stacy Rapacon: Great Funds You Can Own for $500 or Less

Cameron Huddleston: 7 Ways to Save on Home Decor

The Kosher Gourmet by Steve Petusevsky Exploring ingredients as edible-stuffed containers (TWO RECIPES + TIPS & TECHINQUES)

Jewish World Review July 6, 2006 / 10 Tamuz, 5766

MRIs — instead of mammograms — urged for some women

By Judy Peres


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The odds of having one of the known breast cancer genes is about 1 in 800 in the general population. But it can be much higher in certain ethnic groups, such as the 1 in 40 figure for Jews of Eastern European origin




http://www.JewishWorldReview.com | (KRT) High-risk women who rely on mammograms as a weapon against breast cancer may actually increase their chances of getting the disease.


The study looked at 1,600 European women with genetic mutations that predispose them to get breast cancer. Women who reported having had at least one chest X-ray were 54 percent more likely to develop breast cancer than those who had never had one.


This Catch-22, reported in the current issue of the Journal of Clinical Oncology, means women with mutations in BRCA1 or BRCA2 genes might want to consider being screened with magnetic resonance imaging instead of X-rays, doctors said.


It also suggests that women and men with a family history of breast or ovarian cancer might want to consider genetic testing to find out if they carry a mutation before they get any X-rays to the chest area, doctors said.


Exposure to ionizing radiation — the kind that comes from nuclear fallout as well as from X-rays — is known to cause breast cancer. But the risk is small enough for the vast majority of women over 40 that experts still recommend annual screening mammograms.


In women under 40, mammograms are less accurate and the radiation is potentially more dangerous. But those are precisely the women most at risk for hereditary breast cancer.


"Maybe after age 30 the risk of cancer is high enough to justify the potential long-term risk of cumulative radiation," said Dr. Olufumilayo Olopade, director of the cancer risk clinic at the University of Chicago Medical Center. "So we traditionally recommend that high-risk women — especially mutation carriers — start screening with mammography at 25.


"This (study) calls into question, is it possible by starting so young we might increase their risk?"


MRI could eventually become the preferred screening tool for high-risk women, said Olopade, who wrote an editorial accompanying the study. But it's not a perfect solution.


MRI alone can be hard to read and can have a high rate of false-positive results, which lead to unnecessary biopsies, said Dr. Virginia Kaklamani, an expert in breast cancer and cancer genetics at Northwestern University.


So, if a radiologist found something suspicious on an MRI, she said, "I'd probably recommend a mammogram" despite the radiation exposure.


"Until we have more research," Kaklamani said, "younger women with a genetic susceptibility to breast cancer are between a rock and a hard place."


David Goldgar, a genetic epidemiologist at the University of Utah and lead author of the study, said it was too soon to draw conclusions about who should or should not have screening mammograms. He said further research was needed to confirm the results.


The study "is not enough to mandate changes in clinical practice," said Dr. Kathy Albain, director of the breast research program at Loyola University Medical Center in Maywood, Ill. "But I think it's enough to modulate our recommendations for certain patients.


"If you have very young patients who are also BRCA carriers, maybe you don't send them for a chest X-ray at the first cough," she said.


Kaklamani said women known to be mutation carriers might also think twice about getting mammograms before age 35.


The European study did not look at breast X-rays, but the radiation exposure to breast tissue with a mammogram is significantly higher than the exposure with a standard chest X-ray.


The researchers hypothesized that radiation might be particularly dangerous for BRCA mutation carriers because those genes are believed to be responsible for repairing DNA damage. Defective genes would be less able to repair the damage caused by radiation.


Dr. Lydia Usha, who runs the RISC (Rush Inherited Susceptibility to Cancer) Center at Rush University Medical Center in Chicago, said more high-risk women might decide to have prophylactic mastectomies — surgical removal of both breasts — if the study results are confirmed. Most patients don't choose that option now.


Maria Pradd, 38, is one of Kaklamani's patients. A former sales training and development manager, Pradd was diagnosed with breast cancer in 2004. Only after having a lump removed and undergoing treatment did she discover she had a BRCA1 mutation.


Pradd said she will consider having her ovaries removed after she has children, to reduce her risk of getting both ovarian and breast cancer. But she is not interested in prophylactic mastectomy.


She's philosophical about risk, and about how far she's willing to go to reduce it. "I know my chances of having another cancer are greater now," said Pradd. "But I could also walk across the street and get hit by a bus."


She said she would like to add annual MRI to her breast cancer screening regimen, but her medical insurance carrier so far has balked. A breast MRI can cost between $1,000 and $3,000. Mammograms are about a tenth of that.


The odds of having one of the known breast cancer genes is about 1 in 800 in the general population, said Usha. But it can be much higher in certain ethnic groups, such as the 1 in 40 figure for Jews of Eastern European origin.

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© 2006, Chicago Tribune Distributed by Knight Ridder/Tribune Information Services