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April 21, 2014

Andrew Silow-Carroll: Passoverkill? Suggestions to make next year's seders even more culturally sensitive

Sara Israelsen Hartley: Seeking the Divine: An ancient connection in a new context

Christine M. Flowers: Priest's execution in Syria should be call to action

Courtnie Erickson: How to help kids accept the poor decisions of others

Lizette Borreli: A Glass Of Milk A Day Keeps Knee Arthritis At Bay

Lizette Borreli: 5 Health Conditions Your Breath Knows Before You Do

The Kosher Gourmet by Betty Rosbottom Coconut Walnut Bars' golden brown morsels are a beautifully balanced delectable delight

April 18, 2014

Rabbi Yonason Goldson: Clarifying one of the greatest philosophical conundrums in theology

Caroline B. Glick: The disappearance of US will

Megan Wallgren: 10 things I've learned from my teenagers

Lizette Borreli: Green Tea Boosts Brain Power, May Help Treat Dementia

John Ericson: Trying hard to be 'positive' but never succeeding? Blame Your Brain

The Kosher Gourmet by Julie Rothman Almondy, flourless torta del re (Italian king's cake), has royal roots, is simple to make, . . . but devour it because it's simply delicious

April 14, 2014

Rabbi Dr Naftali Brawer: Passover frees us from the tyranny of time

Greg Crosby: Passing Over Religion

Eric Schulzke: First degree: How America really recovered from a murder epidemic

Georgia Lee: When love is not enough: Teaching your kids about the realities of adult relationships

Cameron Huddleston: Freebies for Your Lawn and Garden

Gordon Pape: How you can tell if your financial adviser is setting you up for potential ruin

Dana Dovey: Up to 500,000 people die each year from hepatitis C-related liver disease. New Treatment Has Over 90% Success Rate

Justin Caba: Eating Watermelon Can Help Control High Blood Pressure

The Kosher Gourmet by Joshua E. London and Lou Marmon Don't dare pass over these Pesach picks for Manischewitz!

April 11, 2014

Rabbi Hillel Goldberg: Silence is much more than golden

Caroline B. Glick: Forgetting freedom at Passover

Susan Swann: How to value a child for who he is, not just what he does

Cameron Huddleston: 7 Financial Tasks You Should Tackle Right Now

Sandra Block and Lisa Gerstner: How to Profit From Your Passion

Susan Scutti: A Simple Blood Test Might Soon Diagnose Cancer

Chris Weller: Have A Slow Metabolism? Let Science Speed It Up For You

The Kosher Gourmet by Diane Rossen Worthington Whitefish Terrine: A French take on gefilte fish

April 9, 2014

Jonathan Tobin: Why Did Kerry Lie About Israeli Blame?

Samuel G. Freedman: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Jessica Ivins: A resolution 70 years later for a father's unsettling legacy of ashes from Dachau

Kim Giles: Asking for help is not weakness

Kathy Kristof and Barbara Hoch Marcus: 7 Great Growth Israeli Stocks

Matthew Mientka: How Beans, Peas, And Chickpeas Cleanse Bad Cholesterol and Lowers Risk of Heart Disease

Sabrina Bachai: 5 At-Home Treatments For Headaches

The Kosher Gourmet by Daniel Neman Have yourself a matzo ball: The secrets bubby never told you and recipes she could have never imagined

April 8, 2014

Lori Nawyn: At Your Wit's End and Back: Finding Peace

Susan B. Garland and Rachel L. Sheedy: Strategies Married Couples Can Use to Boost Benefits

David Muhlbaum: Smart Tax Deductions Non-Itemizers Can Claim

Jill Weisenberger, M.S., R.D.N., C.D.E : Before You Lose Your Mental Edge

Dana Dovey: Coffee Drinkers Rejoice! Your Cup Of Joe Can Prevent Death From Liver Disease

Chris Weller: Electric 'Thinking Cap' Puts Your Brain Power Into High Gear

The Kosher Gourmet by Marlene Parrish A gift of hazelnuts keeps giving --- for a variety of nutty recipes: Entree, side, soup, dessert

April 4, 2014

Rabbi David Gutterman: The Word for Nothing Means Everything

Charles Krauthammer: Kerry's folly, Chapter 3

Amy Peterson: A life of love: How to build lasting relationships with your children

John Ericson: Older Women: Save Your Heart, Prevent Stroke Don't Drink Diet

John Ericson: Why 50 million Americans will still have spring allergies after taking meds

Cameron Huddleston: Best and Worst Buys of April 2014

Stacy Rapacon: Great Mutual Funds for Young Investors

Sarah Boesveld: Teacher keeps promise to mail thousands of former students letters written by their past selves

The Kosher Gourmet by Sharon Thompson Anyone can make a salad, you say. But can they make a great salad? (SECRETS, TESTED TECHNIQUES + 4 RECIPES, INCLUDING DRESSINGS)

April 2, 2014

Paul Greenberg: Death and joy in the spring

Dan Barry: Should South Carolina Jews be forced to maintain this chimney built by Germans serving the Nazis?

Mayra Bitsko: Save me! An alien took over my child's personality

Frank Clayton: Get happy: 20 scientifically proven happiness activities

Susan Scutti: It's Genetic! Obesity and the 'Carb Breakdown' Gene

Lecia Bushak: Why Hand Sanitizer May Actually Harm Your Health

Stacy Rapacon: Great Funds You Can Own for $500 or Less

Cameron Huddleston: 7 Ways to Save on Home Decor

The Kosher Gourmet by Steve Petusevsky Exploring ingredients as edible-stuffed containers (TWO RECIPES + TIPS & TECHINQUES)

Jewish World Review

Clinical studies can give you access to breakthrough treatments --- but know the risks

By Harvard Health Letters





JewishWorldReview.com | In January 2007, Debbera Drake got the news every woman dreads. She had stage-four breast cancer. One doctor she'd sought for a second opinion told her she had just two years to live.

"I was traumatized," Drake recalls feeling after hearing the diagnosis. "I thought, 'I love my husband, my family, and my friends. I can't be limited to two years.'"

After Drake underwent chemotherapy, radiation, and surgery, her oncologist, Dr. Beverly Moy at Massachusetts General Hospital, suggested she take part in a clinical trial for a new breast cancer inhibitor drug. In December 2008, she enrolled in the study.

Four years after Drake started taking the experimental therapy, her cancer is stable. At age 67, she's survived three years longer than her original prognosis.

"Dr. Moy said that no one has lived this long with this type of cancer, so I'm now kind of setting the standard," she says.

Of the clinical trial that may have extended her life, she says, "It has given me hope."

WHY TAKE PART IN CLINICAL TRIALS?
For anyone faced with a serious diagnosis, as Drake was, clinical trials can offer an alternative to the current treatments available. Being part of a study gives you access to breakthrough therapies and a highly trained team of doctors, nurses, and technicians to guide you through those therapies. Many trials cover the cost of medical treatment, and some may even compensate you for your participation.

"There are many benefits of participating in clinical trials," says Dr. JoAnn Manson, chief of preventive medicine at Brigham and Women's Hospital (Boston, Mass.), professor of medicine at Harvard Medical School, and principal investigator of VITAL (VITamin D and OmegA-3 TriaL).


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For researchers like Dr. Manson, clinical studies provide a controlled setting in which to compare the effectiveness of new therapies or prevention strategies against those currently in use. What they learn from these studies can be used to develop new and potentially more effective ways to treat or prevent illnesses, helping large numbers of people.

"When people participate in randomized clinical trials, they are advancing science and helping to get important answers," Dr. Manson says.

You don't need to have a life-threatening disease--like Drake did--to take part in a clinical study. In fact, you don't need to be sick at all. Researchers are always looking for healthy study subjects to test strategies for keeping people well and preventing disease.

Women in particular can benefit from taking part in research studies, because they tend to be underrepresented in clinical trials.

"It's very important that women get involved in randomized clinical trials so that researchers can find treatment and prevention strategies that work for women and are tailored to their needs," Dr. Manson says.

TYPES OF STUDIES
If you enroll in a clinical trial, you may hear your doctor refer to it as "randomized" or "observational." Just what do these terms mean?

During a randomized trial, one group of participants is randomly assigned to receive the treatment being studied, while another group (or groups) receives either a different treatment or an inactive pill called a placebo.

If the study is double-blind, neither the participants nor the doctors and nurses involved know which treatment each person is receiving. This prevents anyone involved from biasing the results.

In an observational study, participants aren't given any specific treatment, but researchers observe them to see how their lifestyle habits relate to their health.

WHAT ARE THE RISKS?
Researchers who design and implement clinical studies must follow strict rules that ensure every participant is as safe as possible. Yet despite all the precautions, there's always a risk with new--or even established--treatments that you might have an adverse effect. Those risks can include the side effects of the treatment, as well as the chance that it won't work for you, or that you'll receive a placebo instead of the active therapy.

If you enroll in a study, you'll be asked to sign an informed consent statement, which outlines all of the potential risks involved in participating, as well as the potential benefits.

"You want to be sure that you read the informed consent," Dr. Manson advises. "Be sure you understand what the trial involves and what your participation requires."

To find a clinical trial in your area, visit www.clinicaltrials.gov. Type your condition and location into the search box (for example, "breast cancer AND Atlanta"), and the site will bring up a list of clinical trials that are recruiting in your area.

ASKING THE RIGHT QUESTIONS
Before enrolling in any clinical trial, here are a few key questions to ask the research team:

1. What is the purpose of this study?

2. How will the study benefit me?

3. What are other treatment options?

4. How long is the study?

5. Has this treatment been tested before? What were the results?

6. What kinds of tests and treatments will I receive?

7. How will I know whether the treatment is working?

8. What kinds of follow-up tests and treatments will be done?

9. What are the risks?

10. What is my risk if I get usual care instead of the treatment? - Harvard Women's Health Watch

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© 2012, PRESIDENT AND FELLOWS OF HARVARD COLLEGE. ALL RIGHTS RESERVED. DISTRIBUTED BY TRIBUNE MEDIA SERVICES, INC.

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